Always On USB
In order to use the PokyPow with the motherboard header, you have to activate a USB always on feature in your motherboards UEFI/BIOS. Unfortunately, this is different for all motherboard manufactures.
On my MSI MAG B550M MORTAR WIFI it was called: Resume By USB Device
No USB2.0 motherboard header or USB always on does not work?
You can still use the PokyPow. Use a external power supply and power via the USB-C port.